An essential resource for all scientists researching cellular responses to DNA damage. Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage."