The experience of the editors reflects the book's aim: to present the core biochemical curriculum for medical students integrating clinical relevance throughout. The text has been focused through the selection and weighting of content while maintaining scientific rigour. Each chapter opener shows the overall metabolic chart highlighting the web of metabolic pathways allowing students to orientate themselves. Boxed clinical examples throughout the text take the science into a practical clinical context. Advanced concept boxes give students interested in a particular subject a further level of information. MCQs, patient-oriented problems and short answer questions at the end of each chapter enable the student to assess their understanding.