This book describes the use of different Mathematical Modeling and Soft Computing techniques used in Epidemiology for experiential research in projects such as how infectious diseases progress to show the likely outcome of an epidemic, and to contribute to public health interventions. The book covers mathematical modelling and soft computing techniques study by which diseases spread and to predict the future course of an outbreak and evaluate epidemic control strategies. The book explores the applications covering numerical and analytical solutions, presents basic and advanced concepts for beginners and industry professionals, and incorporates the latest methodologies and challenges using mathematical modeling and soft computing techniques in epidemiology. Primary users of this book include researchers, academicians, post graduate students, and specialists.