Translational bioinformatics (TBI) involves development of storage, analytics and advanced computational methods to harvest knowledge from voluminous biomedical and genomic data into 4P healthcare (proactive, predictive, preventive and participatory). Translational Bioinformatics Applications in Healthcare offers a detailed overview and concepts of TBI, biological and clinical databases, clinical informatics, and pertinent real-case applications. It further illustrates recent advancements, tools, techniques, and applications of TBI in healthcare including IoT potential, toxin databases, medical image analysis and telemedicine applications, analytics of COVID-19 CT-images, viroinformatics and viral diseases, COVID-19 related research. Covers recent technologies such as Blockchain, IoT, Big data analytics, in bioinformatics Presents the role of translational bioinformatic methods in the fields of Viroinformatics, as well as in drug development and repurposing Includes translational healthcare and NGS for clinical applications Illustrates translational medicine systems and its applications in better healthcare Explores medical image analysis with focus on CT-image and novel coronavirus disease detection Aimed at researchers and graduate students in computational biology, data mining and knowledge discovery, algorithms and complexity, and interdisciplinary fields of studies, including bioinformatics, health-informatics, biostatistics, biomedical engineering, and viroinformatics.